Potential Universal Coronavirus Monoclonal Therapeutic? July 26, 2022 0 Mutating coronavirus variant. [Wildpixel/Getty Images] A research team reports discovering a neutralizing monoclonal antibody that it says has the potential to become a universal coronavirus therapy against SARS-CoV-2 and all its variants of concern, including Beta, Gamma, Delta, Epsilon and Omicron. In multiple animal models, the mAb shows effectiveness against the SARS-CoV, the Severe Acute Respiratory Syndrome that emerged in China in 2002, and MERS-CoV, the Middle East Respiratory Syndrome that appeared in Saudi Arabia in 2012, according to the scientists, who had that it also shows effectiveness against several common cold coronaviruses. The mAb targets the S2 stalk region of the viral spike (S) protein that is highly conserved among beta-coronaviruses yet is also essential for the virus to attach and enter cells, leading to infection. The mAb protected against infections when given as an intraperitoneal in